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Open Access Articles- Top Results for GDF1

GDF1

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Identifiers
SymbolsGDF1 ; DORV; DTGA3
External IDsOMIM602880 MGI95683 HomoloGene105644 GeneCards: GDF1 Gene
Orthologs
SpeciesHumanMouse
Entrez265714559
EnsemblENSG00000130283ENSMUSG00000055694
UniProtP27539P20863
RefSeq (mRNA)NM_001492NM_001163282
RefSeq (protein)NP_001483NP_001156754
Location (UCSC)Chr 19:
18.98 – 19.01 Mb
Chr 8:
70.32 – 70.33 Mb
PubMed search[1][2]

Growth differentiation factor-1 (GDF1) is a protein that in humans is encoded by the GDF1 gene.[1]

GDF1 belongs to the transforming growth factor beta superfamily that has a role in left-right patterning and mesoderm induction during embryonic development.[2] It is found in the brain, spinal cord and peripheral nerves of embryos.[1][2]

References

  1. ^ a b Lee SJ (May 1991). "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure". Proc. Natl. Acad. Sci. U.S.A. 88 (10): 4250–4. PMC 51636. PMID 2034669. doi:10.1073/pnas.88.10.4250. 
  2. ^ a b Rankin CT, Bunton T, Lawler AM, Lee SJ (March 2000). "Regulation of left-right patterning in mice by growth/differentiation factor-1". Nat. Genet. 24 (3): 262–5. PMID 10700179. doi:10.1038/73472. 

Further reading

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