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Open Access Articles- Top Results for GJA10

GJA10

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Identifiers
SymbolsGJA10 ; CX62; RP11-63K6.6
External IDsOMIM611924 MGI1339969 HomoloGene7733 IUPHAR: 734 GeneCards: GJA10 Gene
Orthologs
SpeciesHumanMouse
Entrez8469414610
EnsemblENSG00000135355ENSMUSG00000051056
UniProtQ969M2Q9WUS4
RefSeq (mRNA)NM_032602NM_010289
RefSeq (protein)NP_115991NP_034419
Location (UCSC)Chr 6:
90.6 – 90.61 Mb
Chr 4:
32.6 – 32.6 Mb
PubMed search[1][2]

Gap junction alpha-10 protein, also known as connexin-62 (Cx62), is a protein that in humans is encoded by the GJA10 gene.[1]

Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[1][2]

References

  1. ^ a b "Entrez Gene: gap junction protein". 
  2. ^ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. PMID 12881038. doi:10.1080/15419060302063. 

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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