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Open Access Articles- Top Results for GJD2

GJD2

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Identifiers
SymbolsGJD2 ; CX36; GJA9
External IDsOMIM607058 MGI1334209 HomoloGene7734 IUPHAR: 724 GeneCards: GJD2 Gene
RNA expression pattern
File:PBB GE GJA9 221407 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez5736914617
EnsemblENSG00000159248ENSMUSG00000068615
UniProtQ9UKL4O54851
RefSeq (mRNA)NM_020660NM_010290
RefSeq (protein)NP_065711NP_034420
Location (UCSC)Chr 15:
35.04 – 35.05 Mb
Chr 2:
114.01 – 114.01 Mb
PubMed search[1][2]

Gap junction delta-2 protein (GJD2) also known as connexin-36 (Cx36) or gap junction alpha-9 protein (GJA9) and is a protein that in humans is encoded by the GJD2 gene.[1][2]

Function

GJD2, also called connexin-36 (CX36), is a member of the connexin gene family that is expressed predominantly in mammalian neurons. Connexins associate in groups of 6 and are organized radially around a central pore to form connexons. Each gap junction intercellular channel is formed by the conjunction of 2 connexons. See GJB2 for additional background information on connexins.[2]

References

  1. ^ Belluardo N, Trovato-Salinaro A, Mudo G, Hurd YL, Condorelli DF (Oct 1999). "Structure, chromosomal localization, and brain expression of human Cx36 gene". J Neurosci Res 57 (5): 740–52. PMID 10462698. doi:10.1002/(SICI)1097-4547(19990901)57:5<740::AID-JNR16>3.0.CO;2-Z. 
  2. ^ a b "Entrez Gene: GJA9 gap junction protein, alpha 9, 36kDa". 

Further reading

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