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Open Access Articles- Top Results for GJD4

GJD4

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Identifiers
SymbolsGJD4 ; CX40.1; RP11-425A6.2
External IDsOMIM611922 MGI2444990 HomoloGene17692 IUPHAR: 727 GeneCards: GJD4 Gene
Orthologs
SpeciesHumanMouse
Entrez219770225152
EnsemblENSG00000177291ENSMUSG00000036855
UniProtQ96KN9Q8BSD4
RefSeq (mRNA)NM_153368NM_153086
RefSeq (protein)NP_699199NP_694726
Location (UCSC)Chr 10:
35.89 – 35.9 Mb
Chr 18:
9.28 – 9.28 Mb
PubMed search[1][2]

Gap junction delta-4 protein (GJD4), also known as connexin-40.1 (Cx40.1), is a protein that in humans is encoded by the GJD4 gene.[1]

Function

Connexins, such as GJD4, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[1][2]

References

  1. 1.0 1.1 "Entrez Gene: gap junction protein". 
  2. Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. PMID 12881038. doi:10.1080/15419060302063. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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