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Open Access Articles- Top Results for GNAI1

GNAI1

Template:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/row
Identifiers
SymbolsGNAI1 ; Gi
External IDsOMIM139310 MGI95771 HomoloGene74417 ChEMBL: 4741 GeneCards: GNAI1 Gene
RNA expression pattern
File:PBB GE GNAI1 209576 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez277014677
EnsemblENSG00000127955ENSMUSG00000057614
UniProtP63096B2RSH2
RefSeq (mRNA)NM_001256414NM_010305
RefSeq (protein)NP_001243343NP_034435
Location (UCSC)Chr 7:
79.76 – 79.85 Mb
Chr 5:
18.27 – 18.36 Mb
PubMed search[1][2]

Guanine nucleotide-binding protein G(i), alpha-1 subunit is a protein that in humans is encoded by the GNAI1 gene.[1][2]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

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Nicotine Activity on Dopaminergic Neurons edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602". 

Interactions

GNAI1 has been shown to interact with:

References

  1. ^ Bray P, Carter A, Guo V, Puckett C, Kamholz J, Spiegel A et al. (Aug 1987). "Human cDNA clones for an alpha subunit of Gi signal-transduction protein". Proceedings of the National Academy of Sciences of the United States of America 84 (15): 5115–9. PMC 298804. PMID 3110783. doi:10.1073/pnas.84.15.5115. 
  2. ^ "Entrez Gene: GNAI1 Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1". 
  3. ^ Schiaffino MV, d'Addio M, Alloni A, Baschirotto C, Valetti C, Cortese K et al. (Sep 1999). "Ocular albinism: evidence for a defect in an intracellular signal transduction system". Nature Genetics 23 (1): 108–12. PMID 10471510. doi:10.1038/12715. 
  4. ^ a b Kimple RJ, De Vries L, Tronchère H, Behe CI, Morris RA, Gist Farquhar M et al. (Aug 2001). "RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity". The Journal of Biological Chemistry 276 (31): 29275–81. PMID 11387333. doi:10.1074/jbc.M103208200. 
  5. ^ Kimple RJ, Kimple ME, Betts L, Sondek J, Siderovski DP (Apr 2002). "Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits". Nature 416 (6883): 878–81. PMID 11976690. doi:10.1038/416878a. 
  6. ^ Woulfe DS, Stadel JM (Jun 1999). "Structural basis for the selectivity of the RGS protein, GAIP, for Galphai family members. Identification of a single amino acid determinant for selective interaction of Galphai subunits with GAIP". The Journal of Biological Chemistry 274 (25): 17718–24. PMID 10364213. doi:10.1074/jbc.274.25.17718. 
  7. ^ De Vries L, Elenko E, Hubler L, Jones TL, Farquhar MG (Dec 1996). "GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits". Proceedings of the National Academy of Sciences of the United States of America 93 (26): 15203–8. PMC 26381. PMID 8986788. doi:10.1073/pnas.93.26.15203. 
  8. ^ Tall GG, Krumins AM, Gilman AG (Mar 2003). "Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor". The Journal of Biological Chemistry 278 (10): 8356–62. PMID 12509430. doi:10.1074/jbc.M211862200. 
  9. ^ Lee MJ, Evans M, Hla T (May 1996). "The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway". The Journal of Biological Chemistry 271 (19): 11272–9. PMID 8626678. doi:10.1074/jbc.271.19.11272. 

Further reading

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