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Open Access Articles- Top Results for GPR133

GPR133

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Identifiers
SymbolsGPR133 ; PGR25
External IDsOMIM613639 MGI3041203 HomoloGene34616 IUPHAR: 202 GeneCards: GPR133 Gene
Orthologs
SpeciesHumanMouse
Entrez283383243277
EnsemblENSG00000111452ENSMUSG00000044017
UniProtQ6QNK2Q80T32
RefSeq (mRNA)NM_198827NM_001081342
RefSeq (protein)NP_942122NP_001074811
Location (UCSC)Chr 12:
130.95 – 131.14 Mb
Chr 5:
129.1 – 129.2 Mb
PubMed search[1][2]

Probable G-protein coupled receptor 133 is a protein that in humans is encoded by the GPR133 gene.[1][2]

This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.[3][4]

References

  1. "Entrez Gene: GPR133 G protein-coupled receptor 133". 
  2. Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett 531 (3): 407–14. PMID 12435584. doi:10.1016/S0014-5793(02)03574-3. 
  3. Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 1-4419-7912-3. 
  4. Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. PMC 3321182. PMID 22333914. doi:10.1038/emboj.2012.26. 

Further reading

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