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Galanin receptor 1

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Identifiers
SymbolsGALR1 ; GALNR; GALNR1
External IDsOMIM600377 MGI1096364 HomoloGene74396 IUPHAR: 243 ChEMBL: 4894 GeneCards: GALR1 Gene
RNA expression pattern
File:PBB GE GALR1 220821 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez258714427
EnsemblENSG00000166573ENSMUSG00000024553
UniProtP47211P56479
RefSeq (mRNA)NM_001480NM_008082
RefSeq (protein)NP_001471NP_032108
Location (UCSC)Chr 18:
74.96 – 74.98 Mb
Chr 18:
82.39 – 82.41 Mb
PubMed search[1][2]

Galanin receptor 1 (GAL1) is a G-protein coupled receptor encoded by the GALR1 gene.[1]

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-trans membrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the GI/GO family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.[1]

See also

References

External links

  • "Galanin Receptors: GAL1". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading

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sr:Galaninski receptor 3