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Open Access Articles- Top Results for Girisopam

Girisopam

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Girisopam
180px
Systematic (IUPAC) name
1-(3-chlorophenyl)- 7,8-dimethoxy- 4-methyl- 5H-2,3-benzodiazepine
Clinical data
Identifiers
82230-53-3 7pxY
None
PubChem CID 71257
ChemSpider 64387 7pxY
UNII 2LP301A921 7pxY
ChEMBL CHEMBL1915065 7pxN
Chemical data
Formula C18H17ClN2O2
328.79
 14pxN (what is this?)  (verify)

Girisopam[1] (GYKI-51189) is a drug which is a 2,3-benzodiazepine derivative, related to tofisopam.[2] It has selective anxiolytic action with no sedative, anticonvulsant or muscle relaxant effects.[3][4][5]

See also

References

  1. US Patent 4322346
  2. Psychotropics.dk
  3. Andrási F, Horváth K, Sineger E, Berzsenyi P, Borsy J, Kenessey A, Tarr M, Láng T, Kórösi J, Hámori T. Neuropharmacology of a new psychotropic 2,3-benzodiazepine. Arzneimittelforschung. 1987 Oct;37(10):1119-24.
  4. Horváth K, Andrási F, Botka P, Hámori T. Anxiolytic profile of girisopam and GYKI 52,322 (EGIS 6775). Comparison with chlordiazepoxide and buspirone. Acta Physiologica Hungarica. 1992;79(2):153-61.
  5. Horváth EJ, Salamon C, Bakonyi A, Fekete MI, Palkovits M. [(3)H]-girisopam, a novel selective benzodiazepine for the 2, 3-benzodiazepine binding site. Brain Research. Brain Research Protocols. 1999 Jul;4(2):230-5.



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