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Open Access Articles- Top Results for Guanabenz

Guanabenz

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Guanabenz
File:Guanabenz.svg
File:Guanabenz sf.png
Systematic (IUPAC) name
2-(2,6-dichlorobenzylidene)hydrazinecarboximidamide
Clinical data
AHFS/Drugs.com Consumer Drug Information
MedlinePlus a686003
  • US: C (Risk not ruled out)
Pharmacokinetic data
Protein binding 90%
Half-life 6 hours
Identifiers
5051-62-7
None
PubChem CID 5702063
DrugBank DB00629 7pxY
ChemSpider 4642445 7pxY
UNII GGD30112WC 7pxY
KEGG D04375 7pxY
ChEMBL CHEMBL420 7pxY
Chemical data
Formula C8H8Cl2N4
231.081 g/mol
 14pxY (what is this?)  (verify)

Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist of the alpha-2 adrenergic receptor that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).[1][2]

The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness.

Guanabenz can make one drowsy or less alert, therefore driving or operating dangerous machinery is not recommended.

See also

References

  1. ^ Walker BR, Hare LE, Deitch MW (1982). "Comparative antihypertensive effects of guanabenz and clonidine". The Journal of International Medical Research 10: 6–14. PMID 7037502. 
  2. ^ Bonham AC, Trapani AJ, Portis LR, Brody MJ (1984). "Studies on the mechanism of the central antihypertensive effect of guanabenz and clonidine". Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension 2: S543–6. 


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