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Guanabenz
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File:Guanabenz.svg | |
File:Guanabenz sf.png | |
Systematic (IUPAC) name | |
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2-(2,6-dichlorobenzylidene)hydrazinecarboximidamide | |
Clinical data | |
AHFS/Drugs.com | Consumer Drug Information |
MedlinePlus | a686003 |
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Pharmacokinetic data | |
Protein binding | 90% |
Half-life | 6 hours |
Identifiers | |
5051-62-7 | |
None | |
PubChem | CID 5702063 |
DrugBank | DB00629 7px |
ChemSpider | 4642445 7px |
UNII | GGD30112WC 7px |
KEGG | D04375 7px |
ChEMBL | CHEMBL420 7px |
Chemical data | |
Formula | C8H8Cl2N4 |
231.081 g/mol | |
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14px (what is this?) (verify) |
Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist of the alpha-2 adrenergic receptor that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).[1][2]
The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness.
Guanabenz can make one drowsy or less alert, therefore driving or operating dangerous machinery is not recommended.
See also
References
- ^ Walker BR, Hare LE, Deitch MW (1982). "Comparative antihypertensive effects of guanabenz and clonidine". The Journal of International Medical Research 10: 6–14. PMID 7037502.
- ^ Bonham AC, Trapani AJ, Portis LR, Brody MJ (1984). "Studies on the mechanism of the central antihypertensive effect of guanabenz and clonidine". Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension 2: S543–6.
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