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Open Access Articles- Top Results for Guanosine

Guanosine

Not to be confused with Guanine, Guanidine, or Guanfacine.
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Guanosine
Skeletal formula of guanosine
Ball-and-stick model of the guanosine molecule
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IUPAC name
2-Amino-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Other names
Guanine riboside
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This page is a soft redirect. Identifiers

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118-00-3 7pxY
ChEBI CHEBI:16750 7pxY
ChEMBL ChEMBL375655 7pxY
ChemSpider 6544 7pxY
DrugBank DB02857 7pxY
Jmol-3D images Image
KEGG C00387 7pxY
MeSH Guanosine
PubChem Template:Chembox PubChem/format
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C10H13N5O5
Molar mass 283.241
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 14pxY verify (what is10pxY/10pxN?)
Infobox references

Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction, and intracellular signal transduction (cGMP). When guanine is attached by its N9 nitrogen to the C1 carbon of a deoxyribose ring it is known as deoxyguanosine.

The antiviral drug aciclovir, often used in herpes treatment, is structurally similar to guanosine.

Guanosine is required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein.[1]

File:GuanosinN.png
Guanosine with numbered carbons

References