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HES6
Transcription cofactor HES-6 is a protein that in humans is encoded by the HES6 gene.[1][2]
Interactions
HES6 has been shown to interact with TLE1.[3]
References
- ^ Bae S, Bessho Y, Hojo M, Kageyama R (Aug 2000). "The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation". Development 127 (13): 2933–43. PMID 10851137.
- ^ "Entrez Gene: HES6 hairy and enhancer of split 6 (Drosophila)".
- ^ Gao X, Chandra T, Gratton MO, Quélo I, Prud'homme J, Stifani S et al. (Sep 2001). "HES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation program". J. Cell Biol. 154 (6): 1161–71. PMC 2150829. PMID 11551980. doi:10.1083/jcb.200104058.
Further reading
- Bech P, Bolwig TG, Dein E, Jacobsen O, Gram LF (1975). "Quantitative rating of manic states. Correlation between clinical assessment and Biegel's Objective Rating Scale". Acta Psychiatr Scand 52 (1): 1–6. PMID 1155198. doi:10.1111/j.1600-0447.1975.tb00017.x.
- Vasiliauskas D, Stern CD (2000). "Expression of mouse HES-6, a new member of the Hairy/Enhancer of split family of bHLH transcription factors". Mech. Dev. 98 (1-2): 133–7. PMID 11044617. doi:10.1016/S0925-4773(00)00443-3.
- Gao X, Chandra T, Gratton MO, Quélo I, Prud'homme J, Stifani S et al. (2001). "HES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation program". J. Cell Biol. 154 (6): 1161–71. PMC 2150829. PMID 11551980. doi:10.1083/jcb.200104058.
- Swearingen ML, Sun D, Bourner M, Weinstein EJ (2003). "Detection of differentially expressed HES-6 gene in metastatic colon carcinoma by combination of suppression subtractive hybridization and cDNA library array". Cancer Lett. 198 (2): 229–39. PMID 12957362. doi:10.1016/S0304-3835(03)00313-6.
- Gratton MO, Torban E, Jasmin SB, Theriault FM, German MS, Stifani S (2003). "Hes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanisms". Mol. Cell. Biol. 23 (19): 6922–35. PMC 193938. PMID 12972610. doi:10.1128/MCB.23.19.6922-6935.2003.
- Kang SA, Seol JH, Kim J (2005). "The conserved WRPW motif of Hes6 mediates proteasomal degradation". Biochem. Biophys. Res. Commun. 332 (1): 33–6. PMID 15896295. doi:10.1016/j.bbrc.2005.04.089.
- Ball AJ, Abrahamsson AE, Tyrberg B, Itkin-Ansari P, Levine F (2007). "HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion". Biochem. Biophys. Res. Commun. 355 (2): 331–7. PMC 1852427. PMID 17300753. doi:10.1016/j.bbrc.2007.01.153.
- Carey KA, Farnfield MM, Tarquinio SD, Cameron-Smith D (2007). "Impaired expression of Notch signaling genes in aged human skeletal muscle". J. Gerontol. A Biol. Sci. Med. Sci. 62 (1): 9–17. PMID 17301032. doi:10.1093/gerona/62.1.9.
- Scheffer D, Sage C, Corey DP, Pingault V (2007). "Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells". FEBS Lett. 581 (24): 4651–6. PMID 17826772. doi:10.1016/j.febslet.2007.08.059.
External links
- HES6 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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