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HIVEP1

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Identifiers
SymbolsHIVEP1 ; CIRIP; CRYBP1; GAAP; MBP-1; PRDII-BF1; Schnurri-1; ZAS1; ZNF40; ZNF40A
External IDsOMIM194540 MGI96100 HomoloGene1596 ChEMBL: 2909 GeneCards: HIVEP1 Gene
RNA expression pattern
File:PBB GE HIVEP1 204512 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez3096110521
EnsemblENSG00000095951ENSMUSG00000021366
UniProtP15822Q03172
RefSeq (mRNA)NM_002114NM_007772
RefSeq (protein)NP_002105NP_031798
Location (UCSC)Chr 6:
12.01 – 12.17 Mb
Chr 13:
42.05 – 42.19 Mb
PubMed search[1][2]

Zinc finger protein 40 is a protein that in humans is encoded by the HIVEP1 gene.[1][2]

Members of the ZAS family, such as ZAS1 (HIVEP1), are large proteins that contain a ZAS domain, a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specific DNA sequences, including the kappa-B motif (GGGACTTTCC), in the promoters and enhancer regions of several genes and viruses, including human immunodeficiency virus (HIV). ZAS genes span more than 150 kb and contain at least 10 exons, one of which is longer than 5.5 kb (Allen and Wu, 2004).[supplied by OMIM][2]

References

  1. ^ Gaynor RB, Muchardt C, Diep A, Mohandas TK, Sparkes RS, Lusis AJ (Jul 1991). "Localization of the zinc finger DNA-binding protein HIV-EP1/MBP-1/PRDII-BF1 to human chromosome 6p22.3-p24". Genomics 9 (4): 758–61. PMID 2037300. doi:10.1016/0888-7543(91)90371-K. 
  2. ^ a b "Entrez Gene: HIVEP1 human immunodeficiency virus type I enhancer binding protein 1". 

Further reading

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External links


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