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HOXB2

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Identifiers
SymbolsHOXB2 ; HOX2; HOX2H; Hox-2.8; K8
External IDsOMIM142967 MGI96183 HomoloGene37584 GeneCards: HOXB2 Gene
RNA expression pattern
File:PBB GE HOXB2 205453 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez3212103889
EnsemblENSG00000173917ENSMUSG00000075588
UniProtP14652P0C1T1
RefSeq (mRNA)NM_002145NM_134032
RefSeq (protein)NP_002136NP_598793
Location (UCSC)Chr 17:
46.62 – 46.62 Mb
Chr 11:
96.35 – 96.35 Mb
PubMed search[1][2]

Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.[1][2][3]

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer.[3]

See also

References

  1. ^ McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics 7 (3): 460. PMID 1973146. doi:10.1016/0888-7543(90)90186-X. 
  2. ^ Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell 71 (4): 551–3. PMID 1358459. doi:10.1016/0092-8674(92)90588-4. 
  3. ^ a b "Entrez Gene: HOXB2 homeobox B2". 

Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.Template:Gene-17-stub