Open Access Articles- Top Results for Halo nevus

Halo nevus

Halo nevus
Classification and external resources
ICD-10 I78.1, D22 (ILDS D22.L34)
ICD-9 448.1, 216.0-216.9, 757.32
ICD-O 8723/0
OMIM 234300
DiseasesDB 8333
eMedicine derm/174
NCI Halo nevus
Patient UK Halo nevus
MeSH D009508

Halo nevus (also known as "Leukoderma acquisitum centrifugum," "Perinevoid vitiligo," and "Sutton nevus"[1]:689) is a mole that is surrounded by a depigmented ring or 'halo'.


Halo nevi are also known as Sutton's nevi, or leukoderma acquisitum centrifugum. Halo nevi are named such because they are a mole (nevi) that is surrounded by an area of depigmentation that resembles a halo.

Halo nevi are associated with vitiligo. Sometimes the pale (hypopigmented) areas will spontaneous regress, and pigment returns.


The formation of a halo surrounding a nevi is believed to occur when certain white blood cells called CD8+ T lymphocytes destroy the pigment-producing cells of the skin (melanocytes).[2] The cause for the attack is unknown.[3]


File:Halo Nevus zoomed.jpg
Photograph of a halo nevus on a face

Halo nevi are estimated to be present in approximately 1% of the general population, and are found to be more prevalent in people with vitiligo, malignant melanoma,[3] or Turner syndrome.[4] All races and sexes are equally susceptible to this disease, although a familial tendency has been reported. The average age of onset is in a person's teenage years.


As halo nevi are only of cosmetic significance, no treatment is required,[5] and patients will be asymptomatic. Although halo nevi are harmless, it is important to monitor the lesion on regular basis.[6] Watch out for any changes in appearance of existing or new halo nevi. If there is any change in appearance or is associated with pain, itch, and infection, a doctor should be consulted immediately to exclude the possibility of melanoma.

See also


  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. 
  2. ^ Mundinger, Gerhard S. (January 16, 2014). "Halo Phenomenon". New England Journal of Medicine 370 (3): 262–262. doi:10.1056/NEJMicm1306230. 
  3. ^ a b "Halo Nevus -". Retrieved August 4, 2008. 
  4. ^ Halo Nevis at eMedicine
  5. ^ " - Halo Nevis". Retrieved August 4, 2008. 
  6. ^ "DermaTalk - Halo Nevus". 

External links