Open Access Articles- Top Results for Haloxazolam


Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
  •  ?
Pharmacokinetic data
Bioavailability ?
Metabolism Hepatic
Half-life ?
Excretion Renal
59128-97-1 7pxN
PubChem CID 3563
DrugBank DB01476 7pxY
ChemSpider 3442 7pxY
UNII verifiedrevid = 461766568 M448L2V8XP verifiedrevid = 461766568 7pxN
KEGG D01758 7pxN
ChEMBL CHEMBL2104461 7pxN
Chemical data
Formula C17H14BrFN2O2
377.208 g/mol
 14pxN (what is this?)

Haloxazolam (marketed in Japan under the brand name Somelin), is a drug which is a benzodiazepine derivative.[1][2][3] It has similar hypnotic properties as the benzodiazepine drugs triazolam, temazepam, and flunitrazepam and as such is indicated for the treatment insomnia.[4] A study in cats comparing estazolam and haloxazolam found that haloxazolam only affects gamma motor neurons, whereas estazolam affects both alpha and gamma motor neurons.[5]

See also


  1. Tanaka, E; Terada, M; Misawa, S; Wakasugi, C (1996). "Simultaneous determination of twelve benzodiazepines in human serum using a new reversed-phase chromatographic column on a 2-microns porous microspherical silica gel". Journal of Chromatography B 682 (1): 173–8. PMID 8832439. doi:10.1016/0378-4347(96)00121-1. 
  2. "Benzodiazepine Names". Retrieved 2009-04-05. 
  3. Guan, F; Seno, H; Ishii, A; Watanabe, K; Kumazawa, T; Hattori, H; Suzuki, O (1999). "Solid-phase microextraction and GC-ECD of benzophenones for detection of benzodiazepines in urine". Journal of analytical toxicology 23 (1): 54–61. PMID 10022210. doi:10.1093/jat/23.1.54. 
  4. Tan, X; Uchida, S; Matsuura, M; Nishihara, K; Kojima, T (2003). "Long-, intermediate- and short-acting benzodiazepine effects on human sleep EEG spectra". Psychiatry and clinical neurosciences 57 (1): 97–104. PMID 12519461. doi:10.1046/j.1440-1819.2003.01085.x. 
  5. Sakai, Y (1983). "Comparative study on the effects of haloxazolam and estazolam, new sleep inducing drugs, on the alpha- and gamma-motor systems.". Japanese journal of pharmacology 33 (5): 1017–25. PMID 6139494. doi:10.1254/jjp.33.1017. 

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