Open Access Articles- Top Results for Hepatosplenomegaly


Classification and external resources
ICD-10 R16.2
ICD-9 571.8
MedlinePlus 003275
NCI Hepatosplenomegaly
Patient UK Hepatosplenomegaly

Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly). Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease. Systemic venous hypertension can also increase the risk for developing hepatosplenomegaly, which may be seen in those patients with right-sided heart failure.

Common causes

Rare disorders


  1. ^ a b c d e f g h i j medcyclopaedia: Hepatosplenomegaly Retrieved on Nov 23, 2009
  2. ^ a b c d e f g h i j k l m GPNotebook: hepatosplenomegaly Retrieved on Nov 23, 2009
  3. ^ Xavier, Mariana (2010). "Pathogenesis of Brucella spp.". The Open Veterinary Science Journal 4: 109–118. 

External links

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