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Open Access Articles- Top Results for Homochlorcyclizine

Homochlorcyclizine

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Homochlorcyclizine
File:Homochlorcyclizine.png
Systematic (IUPAC) name
1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane
Clinical data
AHFS/Drugs.com International Drug Names
  • (Prescription only)
Oral
Identifiers
848-53-3
None
PubChem CID 3627
ChemSpider 3501
UNII N5MVC31W2N 7pxY
KEGG D08041
ChEMBL CHEMBL151447
Chemical data
Formula C19H23ClN2
314.85 g/mol

Homochlorcyclizine (INN) is an antihistamine which has been marketed in Japan since 1965.[1] It is used in the treatment of allergies and other conditions. It also has some anticholinergic, antidopaminergic, and antiserotonergic properties.[2][3]

See also

References

  1. "Homoclomin Tablets 10 mg" (PDF). Eisai Co. December 2007. Retrieved 2008-07-29. [dead link]
  2. Haraguchi K, Ito K, Kotaki H, Sawada Y, Iga T (June 1997). "Prediction of drug-induced catalepsy based on dopamine D1, D2, and muscarinic acetylcholine receptor occupancies". Drug Metabolism and Disposition: the Biological Fate of Chemicals 25 (6): 675–84. PMID 9193868. 
  3. KIMURA ET, YOUNG PR, RICHARDS RK (1960). "Pharmacologic properties of N-p-chloro-benzhydryl-N'-methyl homopiperazine dihydrochloride (homochlorcyclizine; SA-97), a serotonin antagonist". The Journal of Allergy 31: 237–47. PMID 14409112. 


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