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Open Access Articles- Top Results for Hyper-IgM syndrome type 3

Hyper-IgM syndrome type 3

Hyper-IgM syndrome type 3
File:IgM scheme.svg
Classification and external resources
ICD-10 D80.5
ICD-9 279.05
OMIM 606843
eMedicine ped/2457
NCI Hyper-IgM syndrome type 3
Patient UK Hyper-IgM syndrome type 3
MeSH D053306

Hyper-IgM syndrome type 3 is a form of Hyper IgM syndrome characterized by mutations of the CD40 gene. In this type, Immature B cells cannot receive signal 2 from helper T cells which is necessary to mature into mature B cells.


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