Hyper-IgM syndrome type 3
|Hyper-IgM syndrome type 3|
|Classification and external resources|
|NCI||Hyper-IgM syndrome type 3|
|Patient UK||Hyper-IgM syndrome type 3|
Hyper-IgM syndrome type 3 is a form of Hyper IgM syndrome characterized by mutations of the CD40 gene. In this type, Immature B cells cannot receive signal 2 from helper T cells which is necessary to mature into mature B cells.
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