Open Access Articles- Top Results for Hypochloremia


Classification and external resources
ICD-10 E87.8
ICD-9 276.9
NCI Hypochloremia
Patient UK Hypochloremia

Hypochloremia (or Hypochloraemia) is an electrolyte disturbance in which there is an abnormally low level of the chloride ion in the blood. The normal serum range for chloride is 97 to 107 mEq/L.

It rarely occurs in the absence of other abnormalities.

It can be associated with hypoventilation.[1]

It can be associated with chronic respiratory acidosis.[2]

If it occurs together with metabolic alkalosis (decreased blood acidity) it is often due to vomiting.

It is usually the result of hyponatremia or elevated bicarbonate concentration.

It occurs in cystic fibrosis.


  1. Lavie CJ, Crocker EF, Key KJ, Ferguson TG (October 1986). "Marked hypochloremic metabolic alkalosis with severe compensatory hypoventilation". South. Med. J. 79 (10): 1296–9. PMID 3764530. doi:10.1097/00007611-198610000-00025. 
  2. Levitin H, Branscome W, Epstein FH (December 1958). "The pathogenesis of hypochloremia in respiratory acidosis". J. Clin. Invest. 37 (12): 1667–75. PMC 1062852. PMID 13611033. doi:10.1172/JCI103758. 

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