Open Access Articles- Top Results for Hypogammaglobulinemia


Classification and external resources
ICD-10 D80.0-D80.1
ICD-9 279.00
DiseasesDB 6426
MedlinePlus 001307
eMedicine med/1120 ped/54
NCI Hypogammaglobulinemia
Patient UK Hypogammaglobulinemia
MeSH D000361

Hypogammaglobulinemia is a type of primary immune deficiency disease.[1]

Hypogammaglobulinemia is a characteristic of common variable immunodeficiency.[2]


"Hypogammaglobulinemia" is largely synonymous with "agammaglobulinemia". When the latter term is used (as in "X-linked agammaglobulinemia") it implies that gamma globulins are not merely reduced, but completely absent. Modern assays have allowed most agammaglobulinemias to be more precisely defined as hypogammaglobulinemias,[3] but the distinction is not usually clinically relevant.

"Hypogammaglobulinemia" is distinguished from dysgammaglobulinemia, which is a reduction in some types of gamma globulins, but not others.[4]


Type OMIM Gene
AGM1 601495 IGHM
AGM2 613500 IGLL1
AGM3 613501 CD79A
AGM4 613502 BLNK
AGM5 613506 LRRC8A
AGM6 612692 CD79B


External links

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