Open Access Articles- Top Results for ICI-190,622


File:ICI-190622 structure.png
Systematic (IUPAC) name
Clinical data
103586-12-5 7pxY
PubChem CID 128415
Chemical data
Formula C15H17N5O
283.328 g/mol
 14pxY (what is this?)  (verify)

ICI-190,622 is an anxiolytic drug used in scientific research. It is a pyrazolopyridine derivative, related to other anxiolytic compounds such as tracazolate, and more distantly to zaleplon. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1][2]

See also


  1. ^ Patel JB, Meiners BA, Salama AI, Malick JB, U'Prichard DC, Giles RE, Goldberg ME, Bare TM (April 1988). "Preclinical studies with pyrazolopyridine non-benzodiazepine anxiolytics: ICI 190,622". Pharmacology, Biochemistry, and Behavior 29 (4): 775–9. PMID 2901116. doi:10.1016/0091-3057(88)90205-5. 
  2. ^ Bare TM, McLaren CD, Campbell JB, Firor JW, Resch JF, Walters CP, Salama AI, Meiners BA, Patel JB (December 1989). "Synthesis and structure-activity relationships of a series of anxioselective pyrazolopyridine ester and amide anxiolytic agents". Journal of Medicinal Chemistry 32 (12): 2561–73. PMID 2573731. doi:10.1021/jm00132a011. 

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