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IL13RA2

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Identifiers
SymbolsIL13RA2 ; CD213A2; CT19; IL-13R; IL13BP
External IDsOMIM300130 MGI1277954 HomoloGene534 IUPHAR: 1701 GeneCards: IL13RA2 Gene
RNA expression pattern
File:PBB GE IL13RA2 206172 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez359816165
EnsemblENSG00000123496ENSMUSG00000031289
UniProtQ14627O88786
RefSeq (mRNA)NM_000640NM_008356
RefSeq (protein)NP_000631NP_032382
Location (UCSC)Chr HG1462_PATCH:
114.24 – 114.26 Mb
Chr X:
147.38 – 147.43 Mb
PubMed search[1][2]

Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also known as CD213A2 (cluster of differentiation 213A2), is a membrane bound protein that in humans is encoded by the IL13RA2 gene.[1]

Function

IL-13Rα2 is closely related to IL-13Rα1, a subunit of the interleukin-13 receptor complex. This protein binds IL13 with high affinity, but lacks any significant cytoplasmic domain, and does not appear to function as a signal mediator. It is, however able to regulate the effects of both IL-13 and IL-4, despite the fact it is unable to bind directly to the latter. It is also reported to play a role in the internalization of IL13.[1]

See also

References

Further reading

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External links

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