Open Access Articles- Top Results for Indoramin


Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
26844-12-2 7pxN
PubChem CID 33625
IUPHAR ligand 501
DrugBank DB08950 7pxN
ChemSpider 31014 7pxY
UNII 0Z802HMY7H 7pxY
KEGG D04531 7pxY
ChEMBL CHEMBL279516 7pxY
Chemical data
Formula C22H25N3O
347.454 g/mol
 14pxN (what is this?)  (verify)

Indoramin (trade names Baratol and Doralese) is a piperidine antiadrenergic agent.

It is an alpha-1 selective adrenoceptor antagonist[1] with direct myocardial depression action; therefore, it results in no reflex tachycardia. It is also used in benign prostatic hyperplasia (BPH).[2]

It is commonly synthesized from tryptophol.[3]


Indoramin is commonly prescribed as 20mg tablets when used in BPH.[4]

Side Effects

Drowsiness, dizziness, dry mouth, nasal congestion, headache, fatigue, weight gain, hypotension, postural hypotension, depression, problems with ejaculation, diarrhoea, nausea, increased need to pass urine, and palpitations.[5]


  1. ^ Pierce V, Shepperson NB, Todd MH, Waterfall JF (February 1986). "Investigation into the cardioregulatory properties of the alpha 1-adrenoceptor blocker indoramin". Br. J. Pharmacol. 87 (2): 433–441. PMC 1916533. PMID 3955309. doi:10.1111/j.1476-5381.1986.tb10834.x. 
  2. ^ "Indoramin 20mg tablets". April 20, 2011. Retrieved September 30, 2012. 
  3. ^ Ullman's encyclopedia of Industrial Chemistry, Sixth Edition, 2002.
  4. ^ "Indoramin hydrochloride". National Health Service (UK). Retrieved September 30, 2012. 
  5. ^ "Indoramin 20mg tablets". Retrieved September 30, 2012. 

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