Open Access Articles- Top Results for Indoramin


Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
26844-12-2 7pxN
PubChem CID 33625
IUPHAR ligand 501
DrugBank DB08950 7pxN
ChemSpider 31014 7pxY
UNII 0Z802HMY7H 7pxY
KEGG D04531 7pxY
ChEMBL CHEMBL279516 7pxY
Chemical data
Formula C22H25N3O
347.454 g/mol
 14pxN (what is this?)  (verify)

Indoramin (trade names Baratol and Doralese) is a piperidine antiadrenergic agent.

It is an alpha-1 selective adrenoceptor antagonist[1] with direct myocardial depression action; therefore, it results in no reflex tachycardia. It is also used in benign prostatic hyperplasia (BPH).[2]

It is commonly synthesized from tryptophol.[3]


Indoramin is commonly prescribed as 20mg tablets when used in BPH.[4]

Side Effects

Drowsiness, dizziness, dry mouth, nasal congestion, headache, fatigue, weight gain, hypotension, postural hypotension, depression, problems with ejaculation, diarrhoea, nausea, increased need to pass urine, and palpitations.[5]


  1. Pierce V, Shepperson NB, Todd MH, Waterfall JF (February 1986). "Investigation into the cardioregulatory properties of the alpha 1-adrenoceptor blocker indoramin". Br. J. Pharmacol. 87 (2): 433–441. PMC 1916533. PMID 3955309. doi:10.1111/j.1476-5381.1986.tb10834.x. 
  2. "Indoramin 20mg tablets". April 20, 2011. Retrieved September 30, 2012. 
  3. Ullman's encyclopedia of Industrial Chemistry, Sixth Edition, 2002.
  4. "Indoramin hydrochloride". National Health Service (UK). Retrieved September 30, 2012. 
  5. "Indoramin 20mg tablets". Retrieved September 30, 2012. 

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