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Interleukin 10 receptor, beta subunit

SymbolsIL10RB ; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IL-10R2
External IDsOMIM123889 MGI109380 HomoloGene523 IUPHAR: 1728 GeneCards: IL10RB Gene
RNA expression pattern
File:PBB GE IL10RB 209575 at tn.png
More reference expression data
RefSeq (mRNA)NM_000628NM_008349
RefSeq (protein)NP_000619NP_032375
Location (UCSC)Chr 21:
34.64 – 34.67 Mb
Chr 16:
91.41 – 91.43 Mb
PubMed search[1][2]

Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor. IL10RB is its human gene.[1]

IL10RB has also recently been designated CDW210B (cluster of differentiation W210B).

The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.[1]


Further reading


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