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Open Access Articles- Top Results for Iodocyanopindolol

Iodocyanopindolol

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Iodocyanopindolol
Skeletal formula of iodocyanopindolol
Space-filling model of the iodocyanopindolol molecule
Systematic (IUPAC) name
(RS)-4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3-iodo-1H-indole-2-carbonitrile
Clinical data
Identifiers
85124-14-7 7pxY
None
ChEBI CHEBI:73370 7pxN
Chemical data
Formula C16H20IN3O2
413.25 g/mol
 14pxN (what is this?)  (verify)

Iodocyanopindolol (INN) is a drug related to pindolol which acts as both a β1 adrenoreceptor antagonist and a 5-HT1A receptor antagonist. Its 125I radiolabelled derivative has been widely used in mapping the distribution of beta adrenoreceptors in the body.[1]

References

  1. ^ Brodde OE, Karad K, Zerkowski HR, Rohm N, Reidemeister JC (1983). "Coexistence of beta 1- and beta 2-adrenoceptors in human right atrium. Direct identification by (+/-)-[125I]iodocyanopindolol binding". Circulation Research 53 (6): 752–758. PMID 6139182. doi:10.1161/01.res.53.6.752. 

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