Adverts

Open Access Articles- Top Results for Ipsapirone

Ipsapirone

</th></tr></th></tr>
Ipsapirone
File:Ipsapirone.svg
Systematic (IUPAC) name
9,9-dioxo-8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-
6-thia-8-azabicyclo[4.3.0]nona-1,3,5-trien-7-one
Clinical data
  • Uncontrolled
Oral
Pharmacokinetic data
Half-life 1.3-2.7 hours
Identifiers
95847-70-4 7pxY
None
PubChem CID 56971
IUPHAR ligand 42
ChemSpider 51365 7pxY
UNII 6J9B11MN0K 7pxY
ChEMBL CHEMBL8412 7pxY
Chemical data
Formula C19H23N5O3S
401.484 g/mol
 14pxY (what is this?)  (verify)

Ipsapirone is a selective 5-HT1A receptor partial agonist of the piperazine and azapirone chemical classes.[1] It has antidepressant and anxiolytic effects.[1] Ipsapitone was studied in 3 placebo controlled trials for depression and continues to be used in research.[2]

See also

References

  1. ^ a b Fanelli RJ, Schuurman T, Glaser T, Traber J (1990). "Ipsapirone: a novel anxiolytic and selective 5-HT1A receptor ligand". Progress in clinical and biological research 361: 461–7. PMID 1981264. 
  2. ^ "Azapirones for generalized anxiety disorder.". Cochrane Database Syst Rev. (3): CD006115. Jul 19, 2006. PMID 16856115. doi:10.1002/14651858.CD006115. 


Lua error in package.lua at line 80: module 'Module:Buffer' not found.