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Isoconazole

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Isoconazole
File:Isoconazole.svg
Systematic (IUPAC) name
(RS)-1-[2-[(2,6-Dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
27523-40-6
D01AC05 G01AF07
PubChem CID 3760
DrugBank DB08943 7pxN
ChemSpider 3629
UNII GRI7WFR424 7pxY
KEGG D04624
ChEBI CHEBI:82865 7pxY
ChEMBL CHEMBL1571863
Chemical data
Formula C18H14Cl4N2O
416.127 g/mol

Isoconazole is an azole antifungal drug.[1] Nigerian and British medical researchers found that for foot and vaginal infections, isoconazole has a similar effectiveness to clotrimazole.[2][3]

References

  1. ^ The Merck Index, 12th Edition, 5176
  2. ^ Oyeka, C.A.; Gugnani H.C. (1992). "Isoconazole nitrate versus clotrimazole in foot and nail infections due to Hendersonula toruloidea, Scytalidium hyalinum and dermatophytes.". Mycoses 35 (11-12): 357–61. PMID 1302811. doi:10.1111/j.1439-0507.1992.tb00894.x. 
  3. ^ Cohen, L. (1984). "Single dose treatment of vaginal candidosis: comparison of clotrimazole and isoconazole.". Retrieved 2008-05-23.