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KCNC4

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Identifiers
SymbolsKCNC4 ; C1orf30; HKSHIIIC; KSHIIIC; KV3.4
External IDsOMIM176265 MGI96670 HomoloGene68427 IUPHAR: 551 GeneCards: KCNC4 Gene
RNA expression pattern
File:PBB GE KCNC4 208251 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez374999738
EnsemblENSG00000116396ENSMUSG00000027895
UniProtQ03721Q8R1C0
RefSeq (mRNA)NM_001039574NM_145922
RefSeq (protein)NP_001034663NP_666034
Location (UCSC)Chr 1:
110.75 – 110.83 Mb
Chr 3:
107.44 – 107.46 Mb
PubMed search[1][2]

Potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), also known as Kv3.4, is a human gene.[1]

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.[1]

See also

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Further reading

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