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KCNK1

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Identifiers
SymbolsKCNK1 ; DPK; HOHO; K2P1; K2p1.1; KCNO1; TWIK-1; TWIK1
External IDsOMIM601745 MGI109322 HomoloGene1691 IUPHAR: 513 GeneCards: KCNK1 Gene
Orthologs
SpeciesHumanMouse
Entrez377516525
EnsemblENSG00000135750ENSMUSG00000033998
UniProtO00180O08581
RefSeq (mRNA)NM_002245NM_008430
RefSeq (protein)NP_002236NP_032456
Location (UCSC)Chr 1:
233.75 – 233.81 Mb
Chr 8:
126 – 126.03 Mb
PubMed search[1][2]

Potassium channel subfamily K member 1 is a protein that in humans is encoded by the KCNK1 gene.[1][2][3]

This gene encodes K2P1.1, a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, and it may require other non-pore-forming proteins for activity.[3]

See also

References

  1. ^ Lesage F, Mattei M, Fink M, Barhanin J, Lazdunski M (Dec 1996). "Assignment of the human weak inward rectifier K+ channel TWIK-1 gene to chromosome 1q42-q43". Genomics 34 (1): 153–5. PMID 8661042. doi:10.1006/geno.1996.0259. 
  2. ^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev 57 (4): 527–40. PMID 16382106. doi:10.1124/pr.57.4.12. 
  3. ^ a b "Entrez Gene: KCNK1 potassium channel, subfamily K, member 1". 

Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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