Open Access Articles- Top Results for KIF4A


SymbolsKIF4A ; KIF4; KIF4G1
External IDsOMIM300521 MGI108389 HomoloGene69022 ChEMBL: 6163 GeneCards: KIF4A Gene
RNA expression pattern
File:PBB GE KIF4A 218355 at tn.png
More reference expression data
RefSeq (mRNA)NM_012310NM_008446
RefSeq (protein)NP_036442NP_032472
Location (UCSC)Chr X:
69.51 – 69.64 Mb
Chr X:
100.63 – 100.73 Mb
PubMed search[1][2]

Chromosome-associated kinesin KIF4A is a protein that in humans is encoded by the KIF4A gene.[1][2]

Kinesins, such as KIF4A, are microtubule-based motor proteins that generate directional movement along microtubules. They are involved in many crucial cellular processes, including cell division (Zhu and Jiang, 2005).[supplied by OMIM][2]


KIF4A has been shown to interact with HMG20B[3] and DNMT3B.[4]


  1. ^ Ha MJ, Yoon J, Moon E, Lee YM, Kim HJ, Kim W (Jun 2000). "Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization". Cytogenet Cell Genet 88 (1–2): 41–2. PMID 10773663. doi:10.1159/000015482. 
  2. ^ a b "Entrez Gene: KIF4A kinesin family member 4A". 
  3. ^ Lee, Young Mi; Kim Wankee (Sep 2003). "Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35". Biochem. J. (England) 374 (Pt 2): 497–503. PMC 1223617. PMID 12809554. doi:10.1042/BJ20030452. 
  4. ^ Geiman, Theresa M; Sankpal Umesh T, Robertson Andrea K, Chen Yue, Mazumdar Manjari, Heale Jason T, Schmiesing John A, Kim Wankee, Yokomori Kyoko, Zhao Yingming, Robertson Keith D (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Res. (England) 32 (9): 2716–29. PMC 419596. PMID 15148359. doi:10.1093/nar/gkh589. 

Further reading


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