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Karyolysis

File:Nuclear changes.jpg
Morphological characteristics of karyolysis and other forms of nuclear destruction.

Karyolysis (from Greek κάρυον karyon, "kernel, seed or nucleus", and λύσις lysis from λύειν lyein, "to separate") is the complete dissolution of the chromatin of a dying cell due to the enzymatic degradation by endonucleases. The whole cell will eventually stain uniformly with eosin after karyolysis. It is usually preceded by karyorrhexis and occurs mainly as a result of necrosis, while in apoptosis after karyorrhexis the nucleus usually dissolves into apoptotic bodies.[1]

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References

  1. Cotran; Kumar, Collins (1998). Robbins Pathologic Basis of Disease. Philadelphia: W.B Saunders Company. ISBN 0-7216-7335-X. 

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