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Open Access Articles- Top Results for Leu-enkephalin

Leu-enkephalin

Leu-enkephalin
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IUPAC names
(2R)-2-[[(2R)-2-[[2-[[2-[[(2R)-2-amino-3-
(4-hydroxyphenyl)propanoyl]amino]acetyl]
amino]acetyl]amino]-3-phenylpropanoyl]
amino]-4-methylpentanoic acid
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58822-25-6 7pxY
ChEMBL ChEMBL8234 7pxN
ChemSpider 406229 7pxN
IUPHAR ligand 1613
Jmol-3D images Image
PubChem Template:Chembox PubChem/format
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C28H37N5O7
Molar mass 555.62268 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 14pxN verify (what is10pxY/10pxN?)
Infobox references

Leu-enkephalin is an endogenous opioid peptide neurotransmitter with the amino acid sequence Tyr-Gly-Gly-Phe-Leu that is found naturally in the brains of many animals, including humans. It is one of the two forms of enkephalin; the other is met-enkephalin. The tyrosine residue at position 1 is thought to be analogous to the 3-hydroxyl group on morphine. Leu-enkephalin has agonistic actions at both the μ- and δ-opioid receptors, with significantly greater preference for the latter. It has little to no effect on the κ-opioid receptor.

See also

References

Template:Opioidergics


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