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Open Access Articles- Top Results for Levobunolol

Levobunolol

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Levobunolol
File:Levobunolol structural formulae.png
Systematic (IUPAC) name
(S)-5-{[3-(tert-Butylamino)-2-hydroxypropyl]oxy}-3,4-dihydronaphthalen-1(2H)-one
Clinical data
Trade names Betagan
AHFS/Drugs.com monograph
MedlinePlus a686011
  • C
Topical (eye drops)
Pharmacokinetic data
Half-life 20 hours
Identifiers
47141-42-4 7pxY
S01ED03
PubChem CID 39468
DrugBank DB01210 7pxY
ChemSpider 36089 7pxY
UNII G6317AOI7K 7pxY
KEGG D08115 7pxY
ChEBI CHEBI:6438 7pxY
ChEMBL CHEMBL1201237 7pxN
Chemical data
Formula C17H25NO3
291.385 g/mol
 14pxN (what is this?)  (verify)

Levobunolol (AK-Beta, Liquifilm, Betegan) is a non-selective beta blocker. It is used topically to manage glaucoma.

References

  • Ishibashi T, Yokoi N, Kinoshita S (2003). "Comparison of the effects of topical levobunolol and timolol solution on the human ocular surface.". Cornea 22 (8): 709–15. PMID 14576520. doi:10.1097/00003226-200311000-00001. 
  • Ogasawara H, Yoshida A, Fujio N, Konno S, Ishiko S (1999). "[Effect of topical levobunolol on retinal, optic nerve head, and choroidal circulation in normal volunteers]". Nippon Ganka Gakkai Zasshi 103 (7): 544–50. PMID 10443129. 
  • Leung M, Grunwald J (1997). "Short-term effects of topical levobunolol on the human retinal circulation.". Eye 11 (3): 371–6. PMID 9373479. doi:10.1038/eye.1997.78. 


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