Open Access Articles- Top Results for Levophacetoperane


File:Phacetoperane chemical structure.png
Systematic (IUPAC) name
[(R)-phenyl-[(2R)-piperidin-2-yl]methyl] acetate
Clinical data
  • (Prescription only)
24558-01-8 7pxY
PubChem CID 65715
Chemical data
Formula C14H19NO2
233.31 g/mol
 14pxY (what is this?)  (verify)

Levophacetoperane (Lidépran,Phacétoperane) is a psychostimulant developed by Rhône-Poulenc in the 1950s.[1] The drug has been used as an antidepressant and anorectic.[2][3] It is the reverse ester of methylphenidate. The reverse esters of many drugs which contain an ester group in their structure such as pethidine and cocaine show similar activity to the parent compound.[4]

See also


  1. ^ US Patent 2928835 - New Esters
  2. ^ Delbeke FT, Debackere M. Isolation and detection of methylphenidate, phacetoperane and some other sympatomimetic central nervous stimulants with special reference to doping. I. Gas chromatographic detection procedure with electron capture detection for some secondary amines. Journal of Chromatography. 1975 Mar 26;106(2):412-7.
  3. ^ O'Neil, Maryadele J. (2001). The Merck index: an encyclopedia of chemicals, drugs, and biologicals. Rahway, NJ: Merck Research Laboratories. ISBN 0-911910-13-1. 
  4. ^ Janssen PAJ, Eddy NB. Compounds Related to Pethidine - IV. New General Chemical Methods of Increasing the Analgesic Activity of Pethidine. Journal of Medicinal and Pharmaceutical Chemistry. 1960; 2(1): 31-45.

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