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List of chemotherapeutic agents

This is a list of chemotherapeutic agents (also known as cytotoxic agents) that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), though it might fall in more than one subsection. A full alphabetical listing is included after the categorical listing.

The agents in this list are often combined into chemotherapy regimens for polychemotherapy (combination chemotherapy). For example, the CHOP regimen consists of cyclophosphamide, hydroxydaunorubicin (doxorubicin), vincristine (Oncovin), and prednisone.

Besides chemotherapy, medical oncology (pharmacotherapy for cancer) includes several noncytotoxic classes of therapy, such as hormonal therapy and targeted therapy (biologic therapy). Those agents are described in the relevant articles.

Alkylating agents

Main article: Alkylating agent

Bifunctional Alkylators

Monofunctional Alkylators

Anthracyclines

Main article: anthracycline

Cytoskeletal disruptors (Taxanes)

Main article: Taxane

Epothilones

Main article: epothilone

Histone Deacetylase Inhibitors

Inhibitors of Topoisomerase I

Inhibitors of Topoisomerase II

Kinase inhibitors

Main article: Kinase inhibitor

Nucleotide analogs and precursor analogs

Peptide antibiotics

Platinum-based agents

Retinoids

Vinca alkaloids and derivatives

Main article: Vinca alkaloid

Full alphabetical listing

Comprehensive table

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