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Open Access Articles- Top Results for Lucanthone

Lucanthone

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Lucanthone
150px
Ball-and-stick model of the lucanthone molecule
Systematic (IUPAC) name
1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one
Clinical data
Identifiers
479-50-5 7pxY
None
PubChem CID 10180
DrugBank DB04967 7pxY
ChemSpider 9772 7pxN
UNII FC6D57000M 7pxY
ChEBI CHEBI:51052 7pxN
Chemical data
Formula C20H24N2OS
340.48 g/mol
 14pxN (what is this?)  (verify)

Lucanthone is a drug used in chemotherapy. It is a prodrug and is converted to the active metabolite hycanthone.

Mechanism of action

Hycanthone binds to acetylcholine receptors in the worm and results in increased sensitivity to stimulation by 5-HT causing increase in motility, paired worms are separated and reproduction is stopped. It causes damage of the integument and vitelline duct.



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