Open Access Articles- Top Results for Lymphomatoid papulosis

Lymphomatoid papulosis

Lymphomatoid papulosis
Classification and external resources
ICD-10 L41.2
ICD-O 9718/1
DiseasesDB 33778
eMedicine derm/254
NCI Lymphomatoid papulosis
Patient UK Lymphomatoid papulosis
MeSH D017731

Lymphomatoid papulosis (LyP) is a rare skin disorder. The overall prevalence rate of lymphomatoid papulosis is estimated at 1.2 to 1.9 cases per 1,000,000 population.

This rare condition has only been studied in depth since 1968.[1]


It can appear very similar to anaplastic large cell lymphoma.[2]

Type "A" is CD30 positive, while type "B" is CD30 negative.[3]

It has been described as "clinically benign but histologically malignant."[4]


It can evolve into lymphoma.[5]


It may respond to methotrexate.[6]

See also


  1. ^ Macaulay WL (January 1968). "Lymphomatoid papulosis. A continuing self-healing eruption, clinically benign--histologically malignant". Arch Dermatol 97 (1): 23–30. PMID 5634442. doi:10.1001/archderm.97.1.23. 
  2. ^ El Shabrawi-Caelen L, Kerl H, Cerroni L (April 2004). "Lymphomatoid papulosis: reappraisal of clinicopathologic presentation and classification into subtypes A, B, and C". Arch Dermatol 140 (4): 441–7. PMID 15096372. doi:10.1001/archderm.140.4.441. 
  3. ^ Neal S. Young; Stanton L. Gerson; Katherine A. High (2006). Clinical hematology. Elsevier Health Sciences. pp. 555–. ISBN 978-0-323-01908-8. Retrieved 14 May 2011. 
  4. ^ Maria Proytcheva (14 March 2011). Diagnostic Pediatric Hematopathology. Cambridge University Press. pp. 544–. ISBN 978-0-521-88160-9. Retrieved 15 May 2011. 
  5. ^ Dalle S, Balme B, Thomas L (2006). "Lymphomatoid papulosis localized to the face". Dermatol. Online J. 12 (3): 9. PMID 16638423. 
  6. ^ Magro CM, Crowson AN, Morrison C, Merati K, Porcu P, Wright ED (April 2006). "CD8+ lymphomatoid papulosis and its differential diagnosis". Am. J. Clin. Pathol. 125 (4): 490–501. PMID 16627259. doi:10.1309/NNV4-L5G5-A0KF-1T06.