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MAS1

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Identifiers
SymbolsMAS1 ; MAS; MGRA
External IDsOMIM165180 MGI96918 HomoloGene1782 IUPHAR: 150 GeneCards: MAS1 Gene
RNA expression pattern
File:PBB GE MAS1 208210 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez414217171
EnsemblENSG00000130368ENSMUSG00000068037
UniProtP04201P30554
RefSeq (mRNA)NM_002377NM_008552
RefSeq (protein)NP_002368NP_032578
Location (UCSC)Chr 6:
160.33 – 160.33 Mb
Chr 17:
12.84 – 12.87 Mb
PubMed search[1][2]

MAS proto-oncogene is a protein that in humans is encoded by the MAS1 gene.[1]

The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.[1]

See also

References

Further reading

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