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Open Access Articles- Top Results for MKNK2

MKNK2

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Identifiers
SymbolsMKNK2 ; GPRK7; MNK2
External IDsOMIM605069 MGI894279 HomoloGene49674 IUPHAR: 2105 ChEMBL: 4204 GeneCards: MKNK2 Gene
EC number2.7.11.1
RNA expression pattern
File:PBB GE MKNK2 218205 s at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez287217347
EnsemblENSG00000099875ENSMUSG00000020190
UniProtQ9HBH9Q8CDB0
RefSeq (mRNA)NM_017572NM_021462
RefSeq (protein)NP_060042NP_067437
Location (UCSC)Chr 19:
2.04 – 2.05 Mb
Chr 10:
80.67 – 80.67 Mb
PubMed search[1][2]

MAP kinase-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MKNK2 gene.[1][2]


Interactions

MKNK2 has been shown to interact with MAPK1[3][4] and Eukaryotic translation initiation factor 4 gamma.[3]

References

  1. Slentz-Kesler K, Moore JT, Lombard M, Zhang J, Hollingsworth R, Weiner MP (Oct 2000). "Identification of the human Mnk2 gene (MKNK2) through protein interaction with estrogen receptor beta". Genomics 69 (1): 63–71. PMID 11013076. doi:10.1006/geno.2000.6299. 
  2. "Entrez Gene: MKNK2 MAP kinase interacting serine/threonine kinase 2". 
  3. 3.0 3.1 Scheper, Gert C; Parra Josep L; Wilson Mary; Van Kollenburg Barbara; Vertegaal Alfred C O; Han Ze-Guang; Proud Christopher G (Aug 2003). "The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization". Mol. Cell. Biol. (United States) 23 (16): 5692–705. ISSN 0270-7306. PMC 166352. PMID 12897141. doi:10.1128/MCB.23.16.5692-5705.2003. 
  4. Waskiewicz, A J; Flynn A; Proud C G; Cooper J A (Apr 1997). "Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2". EMBO J. (ENGLAND) 16 (8): 1909–20. ISSN 0261-4189. PMC 1169794. PMID 9155017. doi:10.1093/emboj/16.8.1909. 

Further reading

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