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Open Access Articles- Top Results for Marinobufagenin

Marinobufagenin

Marinobufagenin
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Other names
Marinobufagin, Marinobufagenin
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470-42-8 7pxY
ChemSpider 10142870
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C24H32O5
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Main hazards Toxic
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Marinobufagenin (marinobufagin) is a cardiotonic bufadienolide steroid secreted by the toad Bufo rubescens[1] and other related species such as Bufo marinus. It is a vasoconstrictor with effects similar to digitalis.[2]

References

  1. ^ Cunha Filho, GA; Schwartz, CA; Resck, IS; Murta, MM; Lemos, SS; Castro, MS; Kyaw, C; Pires Jr, OR et al. (2005). "Antimicrobial activity of the bufadienolides marinobufagin and telocinobufagin isolated as major components from skin secretion of the toad Bufo rubescens". Toxicon : official journal of the International Society on Toxinology 45 (6): 777–82. PMID 15804527. doi:10.1016/j.toxicon.2005.01.017. 
  2. ^ Fedorova, OV; Talan, MI; Agalakova, NI; Lakatta, EG; Bagrov, AY (2002). "Endogenous ligand of alpha(1) sodium pump, marinobufagenin, is a novel mediator of sodium chloride--dependent hypertension". Circulation 105 (9): 1122–7. PMID 11877366. doi:10.1161/hc0902.104710. 

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