Open Access Articles- Top Results for Mepivacaine


Systematic (IUPAC) name
(RS)-N-(2,6-dimethylphenyl)- 1-methyl-piperidine-2-carboxamide
Clinical data
AHFS/ Consumer Drug Information
MedlinePlus a603026
  • C, use w/ caution, may cause fetal bradycardia
96-88-8 7pxY
PubChem CID 4062
DrugBank DB00961 7pxY
ChemSpider 3922 7pxY
UNII B6E06QE59J 7pxY
KEGG D08181 7pxY
ChEBI CHEBI:6759 7pxY
Chemical data
Formula C15H22N2O
246.348 g/mol
 14pxY (what is this?)  (verify)

Mepivacaine /mɛˈpɪvəkn/ is a local anesthetic[1] of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Carbocaine and Polocaine.

Mepivacaine became available in the United States in the 1960s.

Mepivacaine is used in any infiltration and regional anesthesia.

It is supplied as the hydrochloride salt of the racemate.[2]


  1. Porto GG, Vasconcelos BC, Gomes AC, Albert D (January 2007). "Evaluation of lidocaine and mepivacaine for inferior third molar surgery" (PDF). Med Oral Patol Oral Cir Bucal 12 (1): E60–4. PMID 17195831. 
  2. Burm AG, Cohen IM, van Kleef JW, Vletter AA, Olieman W, Groen K (January 1997). "Pharmacokinetics of the enantiomers of mepivacaine after intravenous administration of the racemate in volunteers". Anesth. Analg. 84 (1): 85–9. PMID 8989005. doi:10.1097/00000539-199701000-00016. 

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