Adverts

Open Access Articles- Top Results for Mepyramine

Mepyramine

</th></tr>
Mepyramine
File:Mepyramine.svg
Systematic (IUPAC) name
N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine
Clinical data
AHFS/Drugs.com International Drug Names
MedlinePlus a606008
Identifiers
91-84-9 7pxY
59-33-6 (maleate)
R06AC01 D04AA02
PubChem CID 4992
IUPHAR ligand 1220
DrugBank DB06691 7pxN
ChemSpider 4818 7pxY
UNII HPE317O9TL 7pxY
KEGG D08183 7pxY
ChEBI CHEBI:6762 7pxN
ChEMBL CHEMBL511 7pxY
Synonyms N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
Chemical data
Formula C17H23N3O
285.38 g/mol
 14pxN (what is this?)  (verify)

Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H1 receptor.[1] However, it rapidly permeates the brain often causing drowsiness. It also has anticholinergic properties. It is used in over-the-counter combination products to treat the common cold and menstrual symptoms.[2] It is also the active ingredient of the topical antihistamine creams Anthisan and Neoantergan, sold for the treatment of insect bites, stings, and nettle rash.

Synthesis

See also

References

  1. ^ Parsons, Mike E.; Ganellin, C. Robin (January 2006). "Histamine and its receptors". British Journal of Pharmacology 147 (S1): S127–S135. PMC 1760721. PMID 16402096. doi:10.1038/sj.bjp.0706440. 
  2. ^ Active Ingredients for Midol Complete
  3. ^ R.J. Horclois, U.S. Patent 2,502,151 (1950).
  4. ^ Huttrer, C. P.; Djerassi, C.; Beears, W. L.; Mayer, R. L.; Scholz, C. R. (1946). "Heterocyclic amines with antithistaminic activity". Journal of the American Chemical Society 68 (10): 1999–2002. PMID 21001124. doi:10.1021/ja01214a037.  edit
  5. ^ D. Bovet, R. Horclois, F. Walthert, C.R. Soc. Biol., 138, 99 (1944).

Template:Navbox with collapsible sections


Lua error in package.lua at line 80: module 'Module:Buffer' not found. Lua error in package.lua at line 80: module 'Module:Buffer' not found.