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Open Access Articles- Top Results for Metabolite
Advances in Crop Science and TechnologyProduction of Invertase by Aspergillus niger Under Solid State Fermentation Using Orange Fruit Peel as Substrate
Cellular and Molecular BiologyProduction of Secondary Metabolites from Two Penicillium Strains Adapted to Different Temperature Conditions: A Study on Differential Response of Fu
General Medicine: Open AccessPharmacognostic Characterization, Bioactive Compounds and Powder Antioxidant Action of Leaves of Araca (Psidium cattleianum myrtaceae)
Journal of Diabetes & MetabolismMechanism by which Metformin Influence Metabolic Changes in Human: A Systematic-Review
Journal of Traditional Medicine & Clinical NaturopathyFallopia japonica: Bioactive Secondary Metabolites and Molecular Mode of Anticancer
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Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones). A primary metabolite is directly involved in normal "growth", development, and reproduction. Ethylene is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments such as resins and terpenes etc. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.
Examples of primary metabolites produced by industrial microbiology:
|Amino acids||Glutamic acid, aspartic acid|
|Nucleotides||5' guanylic acid|
|Organic acids||Acetic acid, lactic acid|
Metabolites from chemical compounds, whether inherent or pharmaceutical, are formed as part of the natural biochemical process of degrading and eliminating the compounds. The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Profiling metabolites of pharmaceutical compounds, drug metabolism, is an important part of drug discovery, leading to an understanding of any undesirable side effects.
- Secondary metabolite
- Metabolic control analysis, a specific kind of control analysis
- Metabolomics = the study of global metabolite profiles in a system (cell, tissue, or organism) under a given set of conditions.
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