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Open Access Articles- Top Results for Methanandamide

Methanandamide

Methanandamide
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IUPAC name
(5Z,8Z,11Z,14Z)-N-[(1R)-2-hydroxy-1-methylethyl]icosa-5,8,11,14-tetraenamide
Other names
AM-356; Arachidonyl-1'-hydroxy-2'-propylamide
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157182-49-5 7pxN
ChEMBL ChEMBL120526 7pxY
ChemSpider 4881984 7pxY
Jmol-3D images Image
PubChem Template:Chembox PubChem/format
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C23H39NO2
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Methanandamide (AM-356) is a synthetically created stable chiral analog of anandamide.[1] Its effects have been observed to act on the cannabinoid receptors (specifically on CB1 receptors, which are part of the central nervous system) found in different organisms such as mammals, fish, and certain invertebrates (e.g. Hydra).

References

  1. ^ Abadji, V et al. (1994). "(R)-methanandamide: A chiral novel anandamide possessing higher potency and metabolic stability". Journal of Medical Chemistry 37 (12): 1889–93. PMID 8021930. doi:10.1021/jm00038a020. 


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