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Open Access Articles- Top Results for Methoxamine

Methoxamine

Not to be confused with methoxetamine.
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Methoxamine
File:Methoxamine.png
Systematic (IUPAC) name
2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
390-28-3 7pxY
C01CA10
PubChem CID 6082
IUPHAR ligand 483
DrugBank DB00723 7pxN
ChemSpider 5857 7pxY
UNII HUQ1KC1YLI 7pxY
KEGG D08201 7pxY
ChEMBL CHEMBL524 7pxY
Chemical data
Formula C11H17NO3
211.258
 14pxN (what is this?)  (verify)

Methoxamine is an α1-adrenergic receptor agonist,[1] similar in structure to phenylephrine and 2,5-DMA. It was developed by Burroughs-Wellcome in the 1940s.[2] The drug induces vasoconstriction of skin and splanchnic blood vessels, thereby increasing peripheral vascular resistance and raising mean arterial blood pressure. Because of its hypertensive effects, it may evoke a compensatory reflex bradycardia via the baroreceptors.

See also

References

  1. ^ Pazdernik, Thomas L.; Kerecsen, Laszlo (2007) [2003]. "5". In Goljan, Edward F. Pharmacology (PAPERBACK). Rapid Review (Second ed.). Philadelphia, PA: Mosby-Elsevier. p. 39. ISBN 978-0-323-04550-6. 
  2. ^ US Patent 2359707 - DIMETHOXYPHENYL beta-HYDROXY ISOPROPYLAMINE


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