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Open Access Articles- Top Results for Methoxyphenamine

Methoxyphenamine

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Methoxyphenamine
File:Methoxyphenamine.svg
Systematic (IUPAC) name
1-(2-methoxyphenyl)-N-methylpropan-2-amine
Clinical data
AHFS/Drugs.com International Drug Names
  • (Prescription only)
Oral
Identifiers
93-30-1
R03CB02
PubChem CID 4117
ChemSpider 3974
UNII J3Z5SRI26Z 7pxY
Chemical data
Formula C11H17NO
179.26 g/mol

Methoxyphenamine (trade names ASMI, Euspirol, Orthoxine, Ortodrinex, Proasma), also known as 2-methoxy-N-methylamphetamine (OMMA), is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.[1]

Chemistry

Methoxyphenamine was first synthesized at the Upjohn company by Woodruff and co-workers.[2] A later synthesis by Heinzelman, from the same company, corrects the m.p. given for methoxyphenamine hydrochloride in the earlier paper, and describes an improved synthetic procedure, as well as resolution of the racemic methoxyphenamine.[3]

See also

References

  1. ^ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0. 
  2. ^ E. H. Woodruff, J. P. Lambooy and W. E. Burt (1940). "Physiologically active amines. III. Secondary and tertiary β-phenylpropylamines and β-phenylisopropylamines." J. Am. Chem. Soc. 62 922-924.
  3. ^ R. V. Heinzelman (1953). "Physiologically active secondary amines. β-(o-Methoxyphenyl)-isopropyl-N-methylamine and related compounds." J. Am. Chem. Soc. 75 921-925.



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