Adverts

Open Access Articles- Top Results for Monatepil

Monatepil

Monatepil
1 : 1 mixture (racemate)
colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other
This page is a soft redirect. Names

#REDIRECTmw:Help:Magic words#Other
This page is a soft redirect.-

IUPAC name
(RS)-N-(6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-4-[4-(4-fluorophenyl)-1-piperazinyl]butanamide
colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other
This page is a soft redirect. Identifiers#REDIRECTmw:Help:Magic words#Other
This page is a soft redirect.-



103379-03-9 7pxY
ChemSpider 54798 7pxN
Jmol-3D images Image
KEGG D01171 7pxN
PubChem Template:Chembox PubChem/format
colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other
This page is a soft redirect. Properties

#REDIRECTmw:Help:Magic words#Other
This page is a soft redirect.-

C28H30FN3OS
Molar mass 475.620703
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 14pxN verify (what is10pxY/10pxN?)
Infobox references

Monatepil is a calcium channel blocker and α1-adrenergic receptor antagonist used as an antihypertensive.[1]

Synthesis

File:Monatepil synthesis.png
Monatepil synthesis:[2]

References

  1. Sugimoto T, Hosoki K, Karasawa T (July 1995). "Relative contribution of alpha 1-adrenoceptor blocking activity to the hypotensive effect of the novel calcium antagonist monatepil". Journal of Cardiovascular Pharmacology 26 (1): 55–60. PMID 7564365. doi:10.1097/00005344-199507000-00009. 
  2. Kurokawa, M.; Sato, F.; Fujiwara, I.; Hatano, N.; Honda, Y.; Yoshida, T.; Naruto, S.; Mastumoto, J.; Uno, H. (1991). "A new class of calcium antagonists. 2. Synthesis and biological activity of 11-[4-[4-(4-fluorophenyl)-1-piperazinyl]butyryl]amino]-6,11-dihydrodibenzo[b,e]thiepin maleate and related compounds". Journal of Medicinal Chemistry 34 (3): 927. doi:10.1021/jm00107a009.  edit


Lua error in package.lua at line 80: module 'Module:Buffer' not found.