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Open Access Articles- Top Results for Myosin-heavy-chain kinase

Myosin-heavy-chain kinase

myosin heavy chain kinase
Identifiers
EC number 2.7.11.7
CAS number 64763-54-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a myosin-heavy-chain kinase (EC 2.7.11.7) is an enzyme that catalyzes the chemical reaction

ATP + [myosin heavy-chain] <math>\rightleftharpoons</math> ADP + [myosin heavy-chain] phosphate

Thus, the two substrates of this enzyme are ATP and myosin heavy-chain, whereas its two products are ADP and myosin heavy-chain phosphate.

This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[myosin heavy-chain] O-phosphotransferase. Other names in common use include

  • ATP:myosin-heavy-chain O-phosphotransferase
  • calmodulin-dependent myosin heavy chain kinase
  • MHCK
  • MIHC kinase
  • myosin heavy chain kinase
  • myosin I heavy-chain kinase
  • myosin II heavy-chain kinase
  • [myosin-heavy-chain] kinase
  • myosin heavy chain kinase A
  • STK6.

References

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