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NFIA

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Identifiers
SymbolsNFIA ; CTF; NF-I/A; NF1-A; NFI-A; NFI-L
External IDsOMIM600727 MGI108056 HomoloGene4086 GeneCards: NFIA Gene
Orthologs
SpeciesHumanMouse
Entrez477418027
EnsemblENSG00000162599ENSMUSG00000028565
UniProtQ12857Q02780
RefSeq (mRNA)NM_001134673NM_001122952
RefSeq (protein)NP_001128145NP_001116424
Location (UCSC)Chr 1:
61.33 – 61.93 Mb
Chr 4:
97.77 – 98.12 Mb
PubMed search[1][2]

Nuclear factor 1 A-type is a protein that in humans is encoded by the NFIA gene.[1][2]

Nuclear factor I (NFI) proteins constitute a family of dimeric DNA-binding proteins with similar, and possibly identical, DNA-binding specificity. They function as cellular transcription factors and as replication factors for adenovirus DNA replication. Diversity in this protein family is generated by multiple genes, differential splicing, and heterodimerization.[supplied by OMIM][2]

References

  1. ^ Qian F, Kruse U, Lichter P, Sippel AE (Dec 1995). "Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH". Genomics 28 (1): 66–73. PMID 7590749. doi:10.1006/geno.1995.1107. 
  2. ^ a b "Entrez Gene: NFIA nuclear factor I/A". 

Further reading

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External links


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