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Nacolomab tafenatox

Nacolomab tafenatox?
Monoclonal antibody
Type Fab fragment
Source Mouse
Target colorectal tumor antigen C242
Clinical data
Identifiers
150631-27-9 7pxN
None
Chemical data
 14pxN (what is this?)  (verify)

Nacolomab tafenatox is a mouse monoclonal antibody[1] designed for the treatment of colorectal cancer.[citation needed] The antibody itself, nacolomab, is fused with enterotoxin A from Staphylococcus aureus (which is reflected by 'tafenatox' in the drug's name).[1]

File:Fab-superantigen-fusion protein.svg
Schematic image of nacolomab tafenatox.
VH, VL: variable (antigen binding) domains of antibody fragment
CH1, CL: constant domains of antibody fragment
SAg: enterotoxin A (acting as a superantigen)

See also

References


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